UNH Unitedhealth Group Incorporated Managed Care $447.6B n/a n/a n/a n/a MCK McKesson Corporation Drug & Medical Distributors $403.4B 1.2% $5.9B -218.3% · 2y $3.1B COR Cencora Inc. Drug & Medical Distributors $321.3B 0.8% $3.2B 37.8% $3.3B CI The Cigna Group Managed Care $274.9B n/a n/a n/a n/a CAH Cardinal Health Inc. Drug & Medical Distributors $222.6B 0.5% $1.9B 13.7% $4.7B ELV Elevance Health Inc. Managed Care $199.1B n/a n/a n/a n/a CNC Centene Corporation Managed Care $194.8B n/a n/a n/a n/a HUM Humana Inc. Managed Care $129.7B n/a n/a n/a n/a JNJ Johnson & Johnson Pharmaceuticals $94.2B 25.4% $19.7B 22.2% $21.3B HCA HCA Healthcare Inc. Health Care Providers & Services $75.6B 11.7% $9.1B 15.8% $45.5B LLY Eli Lilly and Company Pharmaceuticals $65.2B 24.0% $14.8B 26.6% $35.2B MRK Merck & Company Inc. Common Stock (new) Pharmaceuticals $65.0B 25.9% $13.4B 18.8% $34.7B PFE Pfizer Inc. Pharmaceuticals $62.6B 26.1% $9.1B 11.3% $51.0B ABBV AbbVie Inc. Pharmaceuticals $61.2B 28.0% $18.3B 21.2% $59.7B AZN AstraZeneca PLC Pharmaceuticals $58.7B 17.1% $11.8B 13.5% $19.0B BMY Bristol-Myers Squibb Company Pharmaceuticals $48.2B 18.9% $12.8B 11.9% $34.6B MOH Molina Healthcare Managed Care $45.4B n/a n/a n/a n/a ABT Abbott Laboratories Pharmaceuticals $44.3B 15.8% $8.1B 10.9% $4.0B GSK GSK plc Pharmaceuticals $43.9B 19.2% $8.6B 16.6% $19.2B AMGN Amgen Inc. Biotechnology $36.8B 36.1% $8.1B 17.7% $45.5B MDT Medtronic plc. Medical Devices & Equipment $36.4B 17.8% $5.4B 6.3% $17.0B GILD Gilead Sciences Inc. Biotechnology $29.4B 31.0% $9.5B 15.2% $25.9B TAK Takeda Pharmaceutical Company Limited Pharmaceuticals $28.9B 11.3% $5.4B 3.9% $22.6B MDLN Medline Inc. Medical Devices & Equipment $28.4B 7.8% $1.3B 8.0% · 2y $10.6B 4502 Takeda Pharmaceutical Pharmaceuticals $28.4B 9.4% $5.5B 2.3% $25.7B SYK Stryker Corporation Medical Devices & Equipment $25.1B 18.3% $4.3B 10.3% $11.8B MMM 3M Company Medical Devices & Equipment $24.9B 20.2% $1.4B 21.9% $7.4B BDX Becton Dickinson and Company Medical Devices & Equipment $21.8B 11.6% $2.7B 5.0% $18.5B THC Tenet Healthcare Health Care Providers & Services $21.3B 11.7% $2.5B 18.4% · 3y $10.4B GEHC GE Healthcare Technologies Inc. Medical Devices & Equipment $20.6B 13.4% $1.5B 13.4% $5.5B BSX Boston Scientific Corporation Medical Devices & Equipment $20.1B 14.2% $3.7B 5.2% $9.2B UHS Universal Health Health Care Providers & Services $17.4B 10.8% $1.2B 9.8% $4.6B TEVA Teva Pharmaceutical Industries Limited Pharmaceuticals $17.3B -2.2% $1.1B -2.2% $27.1B IQV IQVIA Holdings Inc. Life Sciences Tools & Services $16.3B 9.2% $2.1B 5.5% $13.6B 4578 Otsuka Holdings Pharmaceuticals $15.6B 9.5% $2.0B 6.4% +$1.9B cash REGN Regeneron Pharmaceuticals Inc. Pharmaceuticals $14.3B 34.6% $4.4B 21.4% +$6.6B cash VTRS Viatris Pharmaceuticals $14.3B 2.5% $1.9B 0.5% $13.1B NVS Novartis AG Pharmaceuticals $14.0B 126.2% · 1y $17.6B — — LH Labcorp Life Sciences Tools & Services $14.0B 11.9% $1.2B 7.9% $5.6B DVA DaVita Health Care Providers & Services $13.6B 14.8% $1.3B 13.4% $9.6B 4503 Astellas Pharma Pharmaceuticals $13.5B 11.4% $3.2B 8.7% $1.8B 4568 Daiichi Sankyo Pharmaceuticals $13.4B 9.2% $1M 7.5% +$1.1B cash HSIC Henry Schein Inc. Drug & Medical Distributors $13.2B 6.1% $573M 12.7% $2.2B BTSG BrightSpring Health Services Inc. Health Care Providers & Services $12.9B 1.7% $395M 3.9% · 2y $2.4B CYH Community Health Systems Inc. Health Care Providers & Services $12.5B 5.8% $208M 4.4% $13.1B VRTX Vertex Pharmaceuticals Incorporated Pharmaceuticals $12.0B 31.8% $3.4B 35.6% +$6.5B cash OSCR Oscar Health Managed Care $11.7B n/a n/a n/a n/a BAX Baxter International Inc. Medical Devices & Equipment $11.2B 9.2% $332M 6.5% $7.5B DGX Quest Diagnostics Life Sciences Tools & Services $11.0B 14.6% $1.4B 10.4% $5.3B ALC Alcon Inc. Medical Devices & Equipment $10.4B 7.0% $2.1B 2.1% $2.7B BHC Bausch Health Companies Inc. Pharmaceuticals $10.3B 5.5% $1.0B 1.8% $19.5B ISRG Intuitive Surgical Inc. Medical Devices & Equipment $10.1B 30.0% $2.5B 15.6% +$5.9B cash BIIB Biogen Inc. Biotechnology $9.9B 34.6% $2.1B 18.3% $3.3B ZTS Zoetis Inc. Pharmaceuticals $9.5B 34.2% $2.4B 25.5% $6.7B SNY Sanofi ADS Pharmaceuticals $9.0B 81.2% · 1y $8.3B 7.6% $6.7B SOLV Solventum Corporation Medical Devices & Equipment $8.3B 20.7% ($10M) 11.7% $4.2B GRFS Grifols S.A. Pharmaceuticals $8.3B 20.4% $771M 9.9% +$427M cash ICLR ICON plc Life Sciences Tools & Services $8.3B 13.3% $759M 16.5% $2.2B ZBH Zimmer Biomet Holdings Inc. Medical Devices & Equipment $8.2B 11.7% $1.5B 3.8% $6.9B 4519 Chugai Pharmaceutical Pharmaceuticals $7.9B 38.9% $2.0B 31.2% — 4543 Terumo Medical Devices & Equipment $7.1B 15.8% $919M 8.7% $626M A Agilent Technologies Inc. Life Sciences Tools & Services $6.9B 19.1% $1.3B 17.1% $1.3B AVTR Avantor Inc. Life Sciences Tools & Services $6.6B 10.0% $495M 6.8% $3.6B 7733 Olympus Medical Devices & Equipment $6.4B 10.8% $284M 12.5% $325M ARDT Ardent Health Inc. Health Care Providers & Services $6.3B 5.3% — 14.4% $390M OGN Organon Pharmaceuticals $6.2B 25.0% $538M 17.3% $8.1B SNN Smith & Nephew SNATS Inc. Medical Devices & Equipment $6.2B 12.1% $852M 11.2% $827M EW Edwards Lifesciences Corporation Medical Devices & Equipment $6.1B 25.7% $1.4B 21.7% +$3.6B cash 7741 Hoya Medical Devices & Equipment $6.0B n/a $1.4B n/a — STE Steris Medical Devices & Equipment $5.9B 16.1% $972M 7.9% $1.5B EHC Encompass Health Health Care Providers & Services $5.9B 15.0% $848M 10.4% $2.4B AGL agilon health inc. Health Care Providers & Services $5.9B -5.4% ($119M) -51.8% +$139M cash OPCH Option Care Health Inc. Health Care Providers & Services $5.6B 4.6% $217M 8.6% $928M SEM Select Medical Holdings Health Care Providers & Services $5.5B 7.6% $206M 7.2% $3.4B ONC BeOne Medicines Ltd. Pharmaceuticals $5.3B -122.3% $986M -45.6% +$3.5B cash PACS PACS Group Inc. Health Care Providers & Services $5.3B 6.3% $349M 20.9% $52M 4523 Eisai Pharmaceuticals $5.2B 7.2% $290M 6.6% +$358M cash RMD ResMed Inc. Medical Devices & Equipment $5.1B 27.1% $1.7B 16.7% +$541M cash INCY Incyte Life Sciences Tools & Services $5.1B 15.0% — 24.4% $16.7B BLCO Bausch + Lomb Corporation Medical Devices & Equipment $5.1B 4.4% ($66M) 1.2% $4.7B ENSG Ensign Group Health Care Providers & Services $5.1B 7.6% — 17.3% +$431M cash ELAN Elanco Animal Health Incorporated Pharmaceuticals $4.7B -1.2% $284M -0.4% $3.5B DXCM DexCom Inc. Medical Devices & Equipment $4.7B 12.1% $1.2B 9.5% $323M ILMN Illumina Inc. Life Sciences Tools & Services $4.3B 18.2% $931M 16.4% +$143M cash IDXX IDEXX Laboratories Inc. Biotechnology $4.3B 26.2% $1.1B 56.8% $519M JAZZ Jazz Pharmaceuticals Pharmaceuticals $4.3B 16.8% $1.3B 8.2% $4.0B PRGO Perrigo Company plc Pharmaceuticals $4.3B 3.9% $145M 1.4% $3.1B HOLX Hologic Medical Devices & Equipment $4.1B 20.6% $998M 12.6% $316M COO The Cooper Companies Inc. Medical Devices & Equipment $4.1B 16.6% $434M 4.8% $2.4B ALGN Align Technology Medical Devices & Equipment $4.0B 19.9% $491M 23.3% +$1.1B cash MTD Mettler-Toledo International Inc. Life Sciences Tools & Services $4.0B 26.1% $905M 43.3% $2.1B CRL Charles River Labs Life Sciences Tools & Services $4.0B 14.7% $518M 9.0% $1.9B ALHC Alignment Healthcare Managed Care $3.9B n/a n/a n/a n/a ALNY Alnylam Pharmaceuticals $3.7B -79.8% $465M -83.2% +$649M cash XRAY DENTSPLY SIRONA Inc. Medical Devices & Equipment $3.7B -6.8% $104M -5.8% $1.9B BRKR Bruker Life Sciences Tools & Services $3.4B 13.2% $43M 17.7% $1.6B ACHC Acadia Healthcare Company Inc. Health Care Providers & Services $3.3B 13.1% ($57M) 5.5% $2.4B SGRY Surgery Partners Inc. Health Care Providers & Services $3.3B 12.4% $196M 6.1% $3.5B BNTX BioNTech SE American Depositary Share Biotechnology $3.3B -42.2% $459M -10.2% +$16.8B cash EXAS Exact Sciences Life Sciences Tools & Services $3.2B -36.6% $357M -13.1% $1.4B AHCO AdaptHealth Corp. Health Care Providers & Services $3.2B 6.6% $219M 3.9% $1.6B BMRN BioMarin Pharmaceuticals $3.2B -1.7% $748M -0.6% +$715M cash BKD Brookdale Senior Living Inc. Health Care Providers & Services $3.2B -1.3% $17M -1.5% $4.0B UTHR United Therapeutics Pharmaceuticals $3.2B 47.5% $1.5B 19.5% +$2.7B cash ASTH Astrana Health Inc. Health Care Providers & Services $3.2B 7.6% $104M 10.6% $609M WAT Waters Corporation Life Sciences Tools & Services $3.2B 28.8% $564M 28.2% $820M 4507 Shionogi Pharmaceuticals $3.2B 35.3% $1.3B 15.1% +$599M cash 4151 Kyowa Kirin Pharmaceuticals $3.1B 11.5% $445M 6.8% · 2y — MMED MiniMed Group Inc. Medical Devices & Equipment $3.1B -5.4% ($353M) -3.5% +$298M cash WST West Pharmaceutical Medical Devices & Equipment $3.1B 19.0% $583M 18.8% +$589M cash ULS UL Solutions Inc. Life Sciences Tools & Services $3.1B 16.2% $403M 27.0% $196M AMRX Amneal Pharmaceuticals Inc. Pharmaceuticals $3.0B 7.9% $270M 2.9% $2.3B GMED Globus Medical Medical Devices & Equipment $2.9B 19.9% $589M 10.5% +$140M cash NBIX Neurocrine Biotechnology $2.9B 13.3% $757M 10.2% +$713M cash 4506 Sumitomo Pharma Pharmaceuticals $2.9B 13.2% $423M 10.2% $850M RVTY Revvity Inc. Life Sciences Tools & Services $2.9B 12.8% $509M 4.1% $2.3B QDEL QuidelOrtho Biotechnology $2.7B 15.2% ($83M) -21.4% · 2y $2.7B FTRE Fortrea Holdings Inc. Life Sciences Tools & Services $2.7B 1.1% $88M 0.8% $878M NVST Envista Holdings Medical Devices & Equipment $2.7B 10.3% $230M 4.4% $237M PODD Insulet Corporation Medical Devices & Equipment $2.7B 6.2% $479M 4.8% $677M BIO Bio-Rad Life Sciences Tools & Services $2.6B 10.2% $375M 3.0% +$331M cash MEDP Medpace Holdings Life Sciences Tools & Services $2.5B 17.6% $682M 27.3% +$497M cash CHE Chemed Health Care Providers & Services $2.5B 14.4% $325M 30.2% $23M TDOC Teladoc Health Inc. Health Care Providers & Services $2.5B -24.6% $285M -7.7% $214M AVAH Aveanna Healthcare Holdings Inc. Health Care Providers & Services $2.4B 0.4% — -16.8% · 2y $1.1B RPRX Royalty Pharma PLC Pharmaceuticals $2.4B 64.5% — 10.2% $8.3B AMED Amedisys Health Care Providers & Services $2.3B 7.0% $215M 6.6% · 2y $74M HIMS Hims & Hers Health Health Care Providers & Services $2.3B -10.2% $246M -9.4% $744M EXEL Exelixis Inc. Biotechnology $2.3B 23.9% $876M 11.1% +$870M cash NTRA Natera Inc. Life Sciences Tools & Services $2.3B -46.0% $174M -62.2% +$793M cash ENOV Enovis Corporation Medical Devices & Equipment $2.2B -4.4% $20M -1.0% $1.3B ICUI ICU Medical Medical Devices & Equipment $2.2B 2.0% $92M 5.5% $977M 2413 M3 Health Care Technology $2.2B 27.1% $395M 32.5% — SRPT Sarepta Pharmaceuticals $2.2B -65.5% ($250M) -25.1% +$111M cash CON Concentra Group Holdings Parent Inc. Health Care Providers & Services $2.2B 15.5% $197M 16.8% $1.5B PRVA Privia Health Group Health Care Providers & Services $2.1B 1.2% — 8.2% +$480M cash QGEN Qiagen N.V. Biotechnology $2.1B 19.2% $453M 6.6% $556M RDNT RadNet Life Sciences Tools & Services $2.0B 4.9% $147M 4.0% $323M TFX Teleflex Medical Devices & Equipment $2.0B 16.6% $1M 7.3% $2.3B MRNA Moderna Inc. Biotechnology $1.9B -121.9% ($2.1B) -34.7% +$2.0B cash CLOV Clover Health Investments Corp. Managed Care $1.9B n/a n/a n/a n/a MD Pediatrix Medical Group Inc. Health Care Providers & Services $1.9B 10.1% $253M 7.8% $256M EVH Evolent Health Health Care Technology $1.9B -12.2% — -6.4% $819M MSA MSA Safety Incorporated Medical Devices & Equipment $1.9B 13.2% $295M 13.2% $416M ITGR Integer Holdings Medical Devices & Equipment $1.9B 11.2% $105M 6.0% $1.2B HCSG Healthcare Services Group Health Care Providers & Services $1.8B 4.4% $139M 15.4% +$168M cash PTCT PTC Therapeutics Inc. Pharmaceuticals $1.7B -55.4% $702M -44.6% +$1.4B cash IART Integra Lifesciences Holdings Corp Medical Devices & Equipment $1.6B 7.4% $6M 4.4% $1.5B LNTH Lantheus Holdings Biotechnology $1.5B 17.2% $354M 23.7% $210M MASI Masimo Medical Devices & Equipment $1.5B 22.3% $198M 30.5% $372M NHC National HealthCare Corporation Health Care Providers & Services $1.5B 5.3% $149M 5.7% +$53M cash MMSI Merit Medical Systems Medical Devices & Equipment $1.5B 6.2% $216M 4.2% $299M NUS Nu Skin Drug & Medical Distributors $1.5B 8.8% $46M 15.9% +$16M cash ALKS Alkermes Pharmaceuticals $1.5B -4.8% $494M -7.5% +$98M cash LFST LifeStance Health Group Inc. Health Care Providers & Services $1.4B -10.2% $110M -9.1% $32M ADUS Addus HomeCare Health Care Providers & Services $1.4B 6.6% $104M 7.8% $122M PEN Penumbra Medical Devices & Equipment $1.4B 0.5% $221M 0.3% +$187M cash HALO Halozyme Biotechnology $1.4B 37.1% $645M 17.1% $2.0B LIVN LivaNova PLC Medical Devices & Equipment $1.4B -3.0% $226M -4.0% +$259M cash CNMD CONMED Medical Devices & Equipment $1.4B 7.9% $151M 5.0% $794M HAE Haemonetics Medical Devices & Equipment $1.3B 10.4% $260M 7.3% $979M PAHC Phibro Animal Health Corporation Pharmaceuticals $1.3B 8.8% $42M 16.3% $235M PGNY Progyny Health Care Providers & Services $1.3B 4.2% $205M 12.9% +$112M cash LKFT Lakefront Biotherapeutics Pharmaceuticals $1.3B -37.1% ($312M) -5.9% +$3.5B cash TEM Tempus AI Inc. Health Care Technology $1.3B -59.8% ($239M) -209.8% · 1y +$396M cash INDV Indivior Pharmaceuticals Inc. Pharmaceuticals $1.2B -2.9% ($37M) — $124M ENLV Enlivex Ltd. Pharmaceuticals $1.2B -1.2% · 1y ($10M) -61.9% +$20M cash TECH Bio-Techne Biotechnology $1.2B 21.4% $257M 9.4% $184M OMCL Omnicell Medical Devices & Equipment $1.2B 2.3% $87M 2.0% +$29M cash TRLV Trulieve Cannabis Corp. Pharmaceuticals $1.2B 12.1% $229M 5.6% +$119M cash SHC Sotera Health Health Care Providers & Services $1.2B 25.2% $192M 6.9% $1.8B NVAX Novavax Inc. Biotechnology $1.1B -87.6% ($250M) -127.7% +$491M cash WAY Waystar Holding Corp. Health Care Technology $1.1B 15.5% $283M 2.9% $1.4B PBH Prestige Consumer Healthcare Pharmaceuticals $1.1B 29.0% $246M 7.9% $930M ACAD ACADIA Pharmaceuticals Inc. Pharmaceuticals $1.1B -43.2% $109M -47.5% +$178M cash LEGN Legend Biotech Corporation Pharmaceuticals $1.0B -198.6% ($110M) -124.9% +$902M cash TNDM Tandem Diabetes Care Medical Devices & Equipment $1.0B -15.0% ($30M) -24.3% $58M GH Guardant Health Inc. Life Sciences Tools & Services $982M -101.3% ($233M) -29.6% $1.1B MDGL Madrigal Pharmaceuticals Inc. Pharmaceuticals $958M -153.9% · 2y ($190M) -61.2% $141M PNTG The Pennant Group Inc. Common Stock Health Care Providers & Services $948M 4.8% $40M 8.7% $157M IONS Ionis Pharmaceuticals Pharmaceuticals $944M -16.9% ($279M) -11.5% +$917M cash USNA USANA Health Sciences Pharmaceuticals $925M 13.2% $9M 57.1% +$158M cash EVO Evotec SE Pharmaceuticals $917M 4.7% ($114M) -0.7% +$48M cash TLRY Tilray Brands Inc. Common Stock Pharmaceuticals $915M -57.0% — -8.9% +$46M cash INSP Inspire Medical Systems Medical Devices & Equipment $912M -28.7% $103M -19.5% +$284M cash ANIP ANI Pharmaceuticals Inc. Pharmaceuticals $883M 8.8% $171M 4.3% $24M BCRX BioCryst Pharmaceuticals Inc. Biotechnology $875M -113.1% $346M -141.8% · 3y +$275M cash WRBY Warby Parker Inc. Medical Devices & Equipment $872M -10.7% $61M -67.0% +$286M cash NEOG Neogen Biotechnology $870M 13.5% $32M 8.1% $608M HRMY Harmony Biosciences Holdings Inc. Pharmaceuticals $868M 27.1% $348M 37.6% +$612M cash INNV InnovAge Holding Corp. Health Care Providers & Services $854M -2.5% $27M -5.6% +$46M cash ARWR Arrowhead Pharmaceuticals Pharmaceuticals $829M -95.5% $157M -51.0% +$12M cash ASND Ascendis Pharma A/S Ordinary Share Pharmaceuticals $829M -76.7% · 3y $61M -171.6% $229M MYGN Myriad Genetics Inc. Biotechnology $825M -17.7% — -14.3% +$30M cash OFIX Orthofix Medical Inc. Common Stock (DE) Medical Devices & Equipment $822M -2.3% ($1M) -3.2% $75M CAI Caris Life Sciences Inc. Life Sciences Tools & Services $812M -62.4% $67M — +$420M cash TLX Telix Pharmaceuticals Limited Pharmaceuticals $804M 3.7% ($43M) 18.4% $263M USPH U.S. Physical Therapy Health Care Providers & Services $781M 12.8% $61M 13.8% $127M COLL Collegium Pharmaceutical Inc. Pharmaceuticals $781M 7.2% $328M 44.0% · 4y +$148M cash ATEC Alphatec Holdings Medical Devices & Equipment $764M -30.2% $3M -46.7% $405M CORT Corcept Therapeutics Incorporated Pharmaceuticals $761M 30.6% $142M 24.6% +$372M cash IRTC iRhythm Technologies Medical Devices & Equipment $747M -25.5% $60M -28.8% $66M EBS Emergent BioSolutions Inc. Pharmaceuticals $743M 12.5% $157M 5.9% $367M RGEN Repligen Corporation Biotechnology $738M 13.4% $94M 4.3% +$225M cash NEO NeoGenomics Inc. Life Sciences Tools & Services $727M -8.5% ($22M) -7.1% $379M PCRX Pacira BioSciences Pharmaceuticals $726M 3.7% $137M 1.8% $134M AMPH Amphastar Pharmaceuticals Inc. Pharmaceuticals $720M 11.0% $121M 9.0% $337M SUPN Supernus Pharmaceuticals Inc. Pharmaceuticals $719M 20.0% $46M 10.7% +$105M cash AVNS Avanos Medical Inc. Medical Devices & Equipment $701M -6.9% $43M -2.9% $158M KNSA Kiniksa Pharmaceuticals International, PLC Pharmaceuticals $678M -9.3% $136M -6.0% +$414M cash RARE Ultragenyx Pharmaceuticals $673M -126.5% ($472M) -91.8% +$421M cash NVCR NovoCure Medical Devices & Equipment $655M -19.4% ($64M) -22.7% $101M DOCS Doximity Health Care Technology $645M 33.0% $326M 16.2% +$219M cash TXG 10x Genomics Inc. Life Sciences Tools & Services $643M -31.9% $130M -42.0% +$474M cash AXSM Axsome Therapeutics Inc. Pharmaceuticals $638M -79.2% ($94M) -4777.7% · 1y +$135M cash TGTX TG Therapeutics Inc. Pharmaceuticals $616M 12.7% · 3y ($25M) -572.0% $104M CDRE Cadre Holdings Inc. Medical Devices & Equipment $610M 11.7% $57M 10.9% $184M OPK OPKO Health Inc. Pharmaceuticals $607M -18.8% ($191M) -8.2% +$18M cash INSM Insmed Incorporated Pharmaceuticals $606M -199.0% ($945M) -138.4% +$889M cash TMDX TransMedics Group Medical Devices & Equipment $605M -68.3% $166M -18.3% +$36M cash UFPT UFP Technologies Inc. Medical Devices & Equipment $603M 11.4% — 11.6% $115M CPRX Catalyst Pharmaceuticals Inc. Pharmaceuticals $589M 37.2% $209M 48.3% +$709M cash ALVO Alvotech Biotechnology $586M -297.3% ($88M) -64.9% $1.1B BVS Bioventus Inc. Medical Devices & Equipment $568M 2.8% $72M -2.7% $243M HCM HUTCHMED (China) Limited Pharmaceuticals $549M -32.7% ($79M) -23.0% +$1.3B cash ATRC AtriCure Medical Devices & Equipment $535M -10.8% $48M -7.7% +$99M cash MIRM Mirum Pharmaceuticals Inc. Pharmaceuticals $521M -42.3% $55M -61.5% +$74M cash VCYT Veracyte Inc. Life Sciences Tools & Services $517M -24.0% $127M -11.5% +$363M cash ADMA ADMA Biologics Inc Biotechnology $510M -106.6% $42M -38.8% $12M GKOS Glaukos Corporation Medical Devices & Equipment $507M -25.2% ($22M) -8.3% $192M TOI The Oncology Institute Inc. Health Care Providers & Services $503M -18.9% ($28M) -55.1% $44M BBIO BridgeBio Pharma Inc. Pharmaceuticals $502M -656.4% ($447M) -154.1% · 1y $1.4B TVTX Travere Therapeutics Pharmaceuticals $491M -83.6% — -35.3% $219M NATR Nature's Sunshine Products Inc. Pharmaceuticals $480M 4.3% $29M 11.9% +$94M cash ZLAB Zai Lab Limited Pharmaceuticals $457M -163.8% ($159M) -103.2% +$690M cash TARS Tarsus Pharmaceuticals Inc. Biotechnology $451M -65.9% ($13M) -41.2% +$345M cash AORT Artivion Inc. Medical Devices & Equipment $441M 3.9% $17M 3.7% · 4y $150M WGS GeneDx Holdings Corp. Health Care Providers & Services $428M -89.2% $24M -43.6% +$119M cash MDXG MiMedx Group Inc Medical Devices & Equipment $419M -0.3% $73M 33.8% +$148M cash INVA Innoviva Inc. Pharmaceuticals $411M 85.6% $196M 44.4% +$80M cash ARDX Ardelyx Inc. Pharmaceuticals $407M -86.5% ($44M) -82.1% $135M ESPR Esperion Therapeutics Inc. Pharmaceuticals $403M -62.8% ($13M) -383.5% · 1y +$16M cash IMCR Immunocore Holdings plc Biotechnology $400M -23.3% ($14M) — +$864M cash KRYS Krystal Biotech Biotechnology $389M 22.6% $195M -21.4% +$492M cash SNDA Sonida Senior Living Inc. Health Care Providers & Services $381M -0.8% ($9M) -4.4% $899M CDNA CareDx Inc. Life Sciences Tools & Services $380M -19.8% — -25.9% +$143M cash TWST Twist Bioscience Corporation Biotechnology $377M -115.4% ($76M) -50.9% +$231M cash PHAR Pharming Group N.V. Pharmaceuticals $376M 6.9% $54M -2.7% · 3y +$145M cash ARQT Arcutis Biotherapeutics Inc. Pharmaceuticals $376M -65.3% ($6M) -56.1% $66M INMD InMode Ltd. Medical Devices & Equipment $370M 35.3% $85M 36.7% +$386M cash MNKD MannKind Corporation Pharmaceuticals $349M -62.3% $14M — $183M CSTL Castle Biosciences Inc. Life Sciences Tools & Services $344M -14.6% $28M -18.4% +$289M cash TCMD Tactile Systems Technology Inc. Medical Devices & Equipment $330M 4.3% $40M 8.9% +$60M cash FLGT Fulgent Genetics Inc. Life Sciences Tools & Services $323M -10.0% ($124M) -2.9% +$48M cash ANGO AngioDynamics Inc. Medical Devices & Equipment $320M -12.3% $508K -8.8% +$54M cash CRMD CorMedix Inc. Pharmaceuticals $312M -1.6% · 2y $174M -201.9% +$142M cash PRCT PROCEPT BioRobotics Corporation Medical Devices & Equipment $308M -93.9% ($55M) -115.2% +$235M cash BLLN BillionToOne Inc. Life Sciences Tools & Services $305M -30.9% $18M — +$439M cash HSTM HealthStream Inc. Health Care Technology $304M 5.8% $60M 4.3% +$36M cash EOLS Evolus Inc. Pharmaceuticals $297M -44.0% ($46M) -141.6% $92M IRWD Ironwood Pharmaceuticals Inc. Pharmaceuticals $296M 27.3% $127M 44.2% $181M RIGL Rigel Pharmaceuticals Inc. Pharmaceuticals $294M -26.7% — -116.5% +$102M cash XERS Xeris Biopharma Holdings Inc. Pharmaceuticals $292M -50.6% — -44.2% $109M AUPH Aurinia Pharmaceuticals Inc Pharmaceuticals $283M -67.7% — -28.3% +$80M cash ADPT Adaptive Biotechnologies Corporation Biotechnology $277M -108.0% ($49M) -31.7% $61M VCEL Vericel Corporation Biotechnology $276M -4.7% $40M -3.7% +$137M cash HROW Harrow Inc. Pharmaceuticals $272M 0.8% $43M -11.5% · 4y $177M VMD Viemed Healthcare Inc. Health Care Providers & Services $270M 9.2% $23M 11.6% +$1M cash LGND Ligand Pharmaceuticals Pharmaceuticals $268M 31.6% $49M 2.5% +$287M cash IOVA Iovance Biotherapeutics Inc. Biotechnology $264M -197.0% · 2y ($336M) -59.5% +$296M cash ARVN Arvinas Inc. Pharmaceuticals $263M -305.8% ($276M) -37.4% +$685M cash OMDA Omada Health Inc. Health Care Providers & Services $260M -25.7% $17M -123.7% · 1y +$222M cash SDGR Schrodinger Inc. Pharmaceuticals $256M -80.8% $12M -37.6% +$395M cash LMAT LeMaitre Vascular Inc. Medical Devices & Equipment $250M 21.6% $74M 12.1% $140M RCUS Arcus Biosciences Inc. Pharmaceuticals $247M -204.5% ($484M) -54.5% +$123M cash ACB Aurora Cannabis Inc. Pharmaceuticals $245M -115.3% $5M -7.4% +$55M cash STAA STAAR Surgical Company Medical Devices & Equipment $239M 4.7% ($40M) 8.8% +$183M cash KIDS OrthoPediatrics Corp. Medical Devices & Equipment $236M -16.9% ($16M) -7.2% $41M AKBA Akebia Therapeutics Inc. Pharmaceuticals $236M -42.3% $68M -115.6% +$137M cash ANAB AnaptysBio Inc. Pharmaceuticals $235M -60.9% $20M -25.2% +$238M cash CERS Cerus Corporation Medical Devices & Equipment $234M -40.9% $3M -42.9% $64M TALK Talkspace Inc. Health Care Providers & Services $229M -28.9% — -3.3% · 2y +$37M cash PBYI Puma Biotechnology Inc Pharmaceuticals $228M 5.5% $42M -58.9% +$75M cash AXGN Axogen Inc. Medical Devices & Equipment $225M -19.9% ($3M) -16.7% $9M IDYA IDEAYA Biosciences Inc. Pharmaceuticals $219M -179.9% ($73M) -22.1% +$639M cash VNDA Vanda Pharmaceuticals Inc. Pharmaceuticals $216M -2.4% ($110M) -0.4% +$85M cash AMRN Amarin Corporation plc Pharmaceuticals $214M -24.3% — -15.1% +$253M cash ESTA Establishment Labs Holdings Inc. Medical Devices & Equipment $211M -33.0% ($57M) -35.7% $172M CTKB Cytek Biosciences Inc. Life Sciences Tools & Services $201M -5.7% ($9M) -5.5% +$91M cash VALN Valneva SE Biotechnology $201M -31.4% ($66M) -42.3% $76M SIBN SI-BONE Inc. Medical Devices & Equipment $201M -36.2% ($6M) -20.6% +$7M cash SRTA Strata Critical Medical Inc. Health Care Providers & Services $197M -36.6% ($59M) -9.0% +$31M cash LFMDP Lifemd, Inc. Health Care Providers & Services $194M -23.9% $7M -137.6% · 2y +$27M cash RYTM Rhythm Pharmaceuticals Inc. Pharmaceuticals $190M -221.1% · 4y ($117M) -67.5% +$281M cash MRVI Maravai LifeSciences Holdings Inc. Pharmaceuticals $186M 16.8% ($71M) -31.8% $75M STOK Stoke Therapeutics Inc. Pharmaceuticals $184M -277.3% $45M -79.3% +$84M cash GLAS Glass House Brands Inc. Pharmaceuticals $182M -21.6% ($4M) -11.9% $69M KMDA Kamada Ltd. Pharmaceuticals $180M 9.8% $24M 11.1% +$99M cash CYRX CryoPort Inc. Pharmaceuticals $176M -44.0% ($25M) -14.2% +$33M cash HTFL Heartflow Inc. Medical Devices & Equipment $176M -48.7% ($59M) -19.8% · 1y +$177M cash PHAT Phathom Pharmaceuticals Inc. Pharmaceuticals $175M -296.8% · 2y ($167M) — $79M SNDX Syndax Pharmaceuticals Inc. Pharmaceuticals $172M -69.8% · 2y ($323M) -63.8% +$44M cash RGNX REGENXBIO Inc. Biotechnology $170M -233.2% ($126M) -46.7% +$230M cash DNA Ginkgo Bioworks Holdings Inc. Biotechnology $170M -246.5% ($179M) -350.6% +$423M cash PACB Pacific Biosciences of California Inc. Life Sciences Tools & Services $160M -146.8% ($114M) -50.6% $617M LQDA Liquidia Corporation Pharmaceuticals $158M -341.3% ($37M) -163.4% +$171M cash AIRS AirSculpt Technologies Inc. Health Care Providers & Services $152M 1.6% $692K -0.9% $48M GRAL GRAIL Inc. Common Stock Life Sciences Tools & Services $147M -382.0% · 1y ($300M) -47.3% · 2y +$250M cash CRON Cronos Group Inc. Common Share Pharmaceuticals $147M -168.7% $12M -23.2% +$832M cash AAPG ASCENTAGE PHARMA GROUP INTERNATIONAL Pharmaceuticals $145M -376.9% ($20M) -53.0% · 2y $115M BEAM Beam Therapeutics Inc. Biotechnology $140M -555.6% ($360M) -63.1% +$1.2B cash NRC NRC Health Life Sciences Tools & Services $137M 29.3% $19M 46.5% $72M XNCR Xencor Inc. Pharmaceuticals $126M -69.2% ($138M) -12.0% $66M GLUE Monte Rosa Therapeutics Inc. Biotechnology $124M -75.5% · 2y ($27M) -131.4% · 2y +$130M cash GYRE Gyre Therapeutics Inc. Pharmaceuticals $117M -25.1% ($180K) -9.4% +$52M cash OGI Organigram Global Inc. Pharmaceuticals $114M -26.0% ($613K) -9.2% $18K IBRX ImmunityBio Inc. Biotechnology $113M -226.0% · 1y ($309M) -50.2% · 4y $82M URGN UroGen Pharma Ltd. Pharmaceuticals $110M -113.7% ($163M) -58.1% · 4y +$38M cash IPSC Century Therapeutics Inc. Biotechnology $109M -15.8% · 1y ($105M) -65.2% +$107M cash MDXH MDxHealth SA Life Sciences Tools & Services $108M -102.3% ($3M) -104.3% $47M TBPH Theravance Biopharma Inc. Pharmaceuticals $107M -343.1% $238M -73.1% $60M ZVRA Zevra Therapeutics Inc. Pharmaceuticals $106M -158.4% ($2M) -127.4% +$478K cash ZYME Zymeworks Inc. Pharmaceuticals $106M -180.7% ($35M) -37.6% +$41M cash STRO Sutro Biopharma Inc. Biotechnology $102M -142.2% — -48.7% +$137M cash BBNX Beta Bionics Inc. Medical Devices & Equipment $100M -71.5% ($52M) -22.1% · 1y +$219M cash NPCE Neuropace Inc. Medical Devices & Equipment $100M -36.6% ($11M) -31.6% +$2M cash BFLY Butterfly Network Inc. Medical Devices & Equipment $98M -263.0% ($16M) -134.4% +$150M cash BLFS BioLife Solutions Inc. Medical Devices & Equipment $96M -9.6% $18M -3.9% +$28M cash KMTS Kestra Medical Technologies Ltd. Medical Devices & Equipment $95M -177.8% ($90M) -497.9% · 2y +$154M cash CBLL CeriBell Inc. Medical Devices & Equipment $89M -65.6% ($42M) -113.0% · 2y +$139M cash CYTK Cytokinetics Pharmaceuticals $88M -312.5% ($535M) -96.9% $165M LAB Standard BioTools Inc. Pharmaceuticals $85M -63.7% ($83M) -28.0% +$66M cash DCTH Delcath Systems Inc. Medical Devices & Equipment $85M -33.4% $22M -127.1% +$38M cash FDMT 4D Molecular Therapeutics Inc. Biotechnology $85M -416.3% ($110M) -41.1% +$403M cash SPRY ARS Pharmaceuticals Inc. Pharmaceuticals $84M -212.9% ($171M) -39.2% +$149M cash NRIX Nurix Therapeutics Inc. Pharmaceuticals $84M -364.7% ($258M) -50.5% +$247M cash IRMD iRadimed Corporation Medical Devices & Equipment $84M 26.4% $24M 50.5% +$51M cash ARCT Arcturus Therapeutics Holdings Inc. Pharmaceuticals $82M -93.0% ($75M) -1913.4% · 1y +$130M cash MGTX MeiraGTx Holdings plc Biotechnology $81M -420.2% ($50M) -134.1% +$16M cash ADCT ADC Therapeutics SA Pharmaceuticals $81M -166.9% ($141M) — +$146M cash ETON Eton Pharmaceuticals Inc. Pharmaceuticals $80M -6.7% $10M -108.2% $5M BNR Burning Rock Biotech Limited Life Sciences Tools & Services $80M -86.6% ($5M) -229.2% +$71M cash CTMX CytomX Therapeutics Inc. Pharmaceuticals $76M -124.3% ($76M) -20.5% · 1y +$10M cash AUTL Autolus Therapeutics PLC Biotechnology $75M -358.9% · 1y ($292M) -192.1% · 2y +$104M cash ABCL AbCellera Biologics Inc. Biotechnology $75M 4.6% ($174M) -18.4% +$129M cash RXRX Recursion Pharmaceuticals Inc. Biotechnology $75M -799.7% ($378M) -105.6% +$734M cash CLLS Cellectis S.A. Biotechnology $73M -341.0% ($42M) -205.6% +$73M cash CGEN Compugen Ltd. Biotechnology $73M -92.0% $31M -37.0% +$100M cash BCYC Bicycle Therapeutics plc Pharmaceuticals $73M -561.0% ($252M) -29.8% · 2y +$597M cash ASMB Assembly Biosciences Inc. Pharmaceuticals $72M -369.2% ($41M) -69.7% +$58M cash VRDN Viridian Therapeutics Inc. Pharmaceuticals $71M -476.8% · 4y ($277M) -1025.4% · 2y +$825M cash FOCL EDAP TMS S.A. Medical Devices & Equipment $71M -33.5% · 2y ($18M) -111.5% · 2y +$2M cash PSNL Personalis Inc. Life Sciences Tools & Services $70M -80.7% ($79M) -48.4% +$235M cash VIR Vir Biotechnology Inc. Biotechnology $69M -544.0% ($397M) -44.7% +$461M cash NTLA Intellia Therapeutics Inc. Biotechnology $68M -282.5% ($396M) -44.5% +$450M cash KURA Kura Oncology Inc. Pharmaceuticals $67M -404.2% · 2y ($65M) -76.8% +$139M cash CCM Concord Medical Services Holdings Ltd Health Care Providers & Services $67M -129.4% ($38M) -37.4% $402M MESO Mesoblast Limited Biotechnology $65M -488.4% ($61M) -11.1% +$3M cash ENTA Enanta Pharmaceuticals Inc. Pharmaceuticals $65M -73.4% ($32M) -17.1% +$32M cash ELMD Electromed Inc. Medical Devices & Equipment $64M 10.8% $11M 11.1% +$14M cash FBIOP Fortress Biotech, Inc. Pharmaceuticals $63M -271.4% — -372.1% $5M NUVB Nuvation Bio Inc. Pharmaceuticals $63M -338.7% · 1y ($175M) -89.1% +$482M cash TNGX Tango Therapeutics Inc. Pharmaceuticals $62M -329.3% ($140M) -47.3% +$343M cash APT Alpha Pro Tech Ltd. Medical Devices & Equipment $59M 6.7% $2M 9.3% +$17M cash MASS 908 Devices Inc. Life Sciences Tools & Services $56M -72.8% ($25M) -76.0% +$97M cash NKTR Nektar Therapeutics Pharmaceuticals $55M -265.8% ($209M) -46.0% $240M AGIO Agios Pharmaceuticals Inc. Pharmaceuticals $54M -384.0% ($377M) -43.7% +$89M cash PLX Protalix BioTherapeutics Inc. (DE) Biotechnology $53M -23.5% ($14M) -0.6% · 4y $14M XOMA XOMA Royalty Corporation Pharmaceuticals $52M -21.1% — -15.7% $26M OCUL Ocular Therapeutix Inc. Pharmaceuticals $52M -224.4% ($209M) -707.5% · 3y +$666M cash LXRX Lexicon Pharmaceuticals Inc. Pharmaceuticals $50M -160.5% ($68M) -62.9% +$42M cash SI Shoulder Innovations Inc. Medical Devices & Equipment $47M -51.0% · 2y ($32M) -16.1% · 1y +$12M cash BWAY BrainsWay Ltd. Medical Devices & Equipment $46M -26.5% $22M -142.7% +$66M cash PTGX Protagonist Therapeutics Inc. Pharmaceuticals $46M -207.1% $56M -56.4% +$558M cash SEPN Septerna Inc. Pharmaceuticals $46M 612.8% · 2y $110M -27.9% · 2y +$391M cash FENC Fennec Pharmaceuticals Inc. Biotechnology $45M -14.1% · 3y — -167.0% · 1y +$17M cash AQST Aquestive Therapeutics Inc. Pharmaceuticals $45M -72.6% ($53M) -285.9% · 1y +$76M cash WVE Wave Life Sciences Ltd. Pharmaceuticals $43M -310.1% ($188M) — +$602M cash SSII SS Innovations International Inc. Medical Devices & Equipment $42M -149.0% ($20M) -85.6% +$2M cash KYMR Kymera Therapeutics Inc. Biotechnology $39M -277.5% ($234M) -25.7% +$357M cash NBTX Nanobiotix S.A. Pharmaceuticals $38M -53.6% ($39M) — +$61M cash CLPT ClearPoint Neuro Inc. Medical Devices & Equipment $37M -75.4% ($24M) -228.1% $3M CCCC C4 Therapeutics Inc. Biotechnology $36M -336.1% ($99M) -50.0% +$75M cash XFOR X4 Pharmaceuticals Inc. Biotechnology $35M -247.4% · 1y ($86M) -175.4% +$142M cash BHST BioHarvest Sciences Inc. Pharmaceuticals $35M -27.7% ($9M) -181.8% · 1y +$23M cash EYPT EyePoint Inc. Life Sciences Tools & Services $31M -240.6% ($242M) -113.4% +$277M cash VSTM Verastem Inc. Pharmaceuticals $31M -452.5% — -78.2% +$129M cash PRE Prenetics Global Limited Pharmaceuticals $31M -238.7% ($30M) -28.9% +$52M cash BGM BGM Group Ltd. Pharmaceuticals $27M 4.2% ($6M) 4.9% +$11M cash ALMS Alumis Inc. Pharmaceuticals $24M — ($370M) -169.4% · 1y +$309M cash BDMD Baird Medical Investment Holdings Ltd Medical Devices & Equipment $23M 38.3% ($1M) 26.8% $9M NAMS NewAmsterdam Pharma Company N.V. Pharmaceuticals $23M -195.2% · 2y ($148M) -46.4% · 2y +$636M cash DRIO DarioHealth Corp. Medical Devices & Equipment $22M -257.7% ($26M) -83.5% $14M SLGL Sol-Gel Technologies Ltd. Pharmaceuticals $19M -108.7% $275K -49.1% +$24M cash OABI OmniAb Inc. Life Sciences Tools & Services $19M -203.2% ($37M) -18.4% +$26M cash MDWD MediWound Ltd. Pharmaceuticals $17M -81.8% ($17M) -61.2% +$9M cash PROF Profound Medical Corp. Medical Devices & Equipment $16M -309.6% ($38M) -256.8% +$53M cash QURE uniQure N.V. Pharmaceuticals $16M -334.3% ($178M) -87.0% +$29M cash IVA Inventiva S.A. Pharmaceuticals $16M -468.9% · 3y — -395.9% — RLAY Relay Therapeutics Inc. Biotechnology $15M -67.5% · 1y ($236M) -45.8% +$84M cash IRD Opus Genetics Inc. Pharmaceuticals $14M -139.8% — -506.0% · 2y +$44M cash ABUS Arbutus Biopharma Corporation Pharmaceuticals $14M -430.5% ($40M) -84.6% +$91M cash CV CapsoVision Inc. Medical Devices & Equipment $14M -178.8% · 2y ($23M) -152.0% · 1y — NNOX NANO-X IMAGING LTD Medical Devices & Equipment $13M -600.8% · 3y ($41M) -42.9% +$61M cash EVMN Evommune Inc. Pharmaceuticals $13M -623.6% · 1y ($77M) -39.7% · 1y +$149M cash PRLD Prelude Therapeutics Incorporated Pharmaceuticals $12M -861.3% · 1y ($56M) -170.1% · 2y +$103M cash CBIO Crescent Biopharma Inc. Pharmaceuticals $11M -74.1% ($72M) -1404.0% · 1y +$213M cash IPHA Innate Pharma S.A. ADS Biotechnology $10M -90.8% ($61M) -1025.6% · 3y +$39M cash ACOG Alpha Cognition Inc. Biotechnology $10M -221.7% · 1y ($20M) — +$65M cash JANX Janux Therapeutics Inc. Pharmaceuticals $10M -779.0% · 1y ($83M) -13.8% +$967M cash ZBIO Zenas BioPharma Inc. Pharmaceuticals $10M -74.3% · 1y ($172M) -144.0% · 1y +$265M cash TSHA Taysha Gene Therapies Inc. Biotechnology $10M -468.8% · 1y ($94M) — +$270M cash PGEN Precigen Inc. Pharmaceuticals $10M -334.4% ($90M) -71.5% $39M PRTA Prothena Corporation plc Pharmaceuticals $10M -209.1% ($164M) -785.8% · 1y +$308M cash BIOA BioAge Labs Inc. Pharmaceuticals $9M — ($82M) -85.4% · 1y +$278M cash NSPR InspireMD Inc. Medical Devices & Equipment $9M -351.3% ($37M) -84.7% +$49M cash NNNN Anbio Biotechnology Biotechnology $9M 36.3% — 37.5% +$12M cash ROIV Roivant Sciences Ltd. Pharmaceuticals $8M 13746.9% · 1y ($759M) -26.6% · 2y +$3.8B cash ACRS Aclaris Therapeutics Inc. Pharmaceuticals $8M -534.9% · 4y ($47M) -72.6% +$9M cash CRNX Crinetics Pharmaceuticals Inc. Pharmaceuticals $8M -446.3% · 1y ($382M) -46.3% +$1.0B cash ADAG Adagene Inc. Pharmaceuticals $8M -279.5% · 3y ($16M) — +$73M cash EVAX Evaxion A/S American Depositary Share Biotechnology $8M -281.6% · 2y ($7M) -1319.6% +$9M cash IMMP Immutep Limited Pharmaceuticals $7M -544.6% ($44M) -182.8% +$91M cash OVID Ovid Therapeutics Inc. Pharmaceuticals $7M -585.2% ($38M) -63.6% +$13M cash IMNM Immunome Inc. Pharmaceuticals $7M -781.4% · 1y ($193M) -523.5% · 2y +$653M cash EUDA EUDA Health Holdings Limited Health Care Providers & Services $7M -106.9% ($3M) -160.8% · 1y +$376K cash FATE Fate Therapeutics Inc. Biotechnology $7M -388.6% ($112M) -56.3% +$189M cash ABEO Abeona Therapeutics Inc. Biotechnology $6M -814.2% · 1y ($79M) -80.1% +$171M cash DBVT DBV Technologies S.A. Biotechnology $6M -486.0% · 1y ($122M) -1205.9% · 3y +$193M cash PRME Prime Medicine Inc. Biotechnology $5M -17.9% · 1y ($167M) -176.8% +$63M cash OCGN Ocugen Inc. Biotechnology $4M — ($57M) -783.8% · 2y $10M CPHI China Pharma Holdings Inc. Pharmaceuticals $4M -65.3% $89K -29.3% $5M ATAI AtaiBeckley Inc. Pharmaceuticals $4M — ($104M) -220.3% · 2y +$79M cash CGON CG Oncology Inc. Biotechnology $4M — ($132M) -19.9% · 2y +$739M cash RADX Radiopharm Theranostics Limited Pharmaceuticals $4M — ($37M) -219.2% +$29M cash CRSP CRISPR Therapeutics AG Biotechnology $4M -21.9% · 4y ($346M) -27.3% +$1.9B cash UPB Upstream Bio Inc. Pharmaceuticals $3M — ($133M) -47.9% · 2y +$342M cash ABSI Absci Corporation Life Sciences Tools & Services $3M -278.3% · 1y ($94M) -56.1% +$140M cash DNTH Dianthus Therapeutics Inc. Pharmaceuticals $2M — ($129M) -54.3% +$404M cash ORMP Oramed Pharmaceuticals Inc. Pharmaceuticals $2M -546.8% ($9M) -35.5% +$51M cash AVR Anteris Technologies Global Corp. Medical Devices & Equipment $2M — ($80M) — +$13M cash CLDX Celldex Therapeutics Inc. Biotechnology $2M -854.1% · 1y ($214M) -38.3% +$507M cash ONMD OneMedNet Corp Life Sciences Tools & Services $1M -671.2% ($8M) — $915K PLUR Pluri Inc. Biotechnology $1M -819.1% · 1y ($19M) -68.3% $18M INBX Inhibrx Biosciences Inc. Biotechnology $1M — ($130M) — +$24M cash SXTC China SXT Pharmaceuticals Inc. Pharmaceuticals $1M -88.2% ($4M) -57.9% +$28M cash STTK Shattuck Labs Inc. Pharmaceuticals $1M -253.5% · 3y ($40M) -103.8% +$54M cash PROK ProKidney Corp. Biotechnology $893K — ($127M) — +$109M cash SLN Silence Therapeutics PLC Pharmaceuticals $559K -203.5% ($62M) -177.1% +$85M cash QUCY Quantum Cyber N.V. Pharmaceuticals $537K — ($11M) — +$889K cash MREO Mereo BioPharma Group plc Pharmaceuticals $500K -284.2% · 1y ($31M) — +$41M cash PLSE Pulse Biosciences Inc Common Stock (DE) Medical Devices & Equipment $350K — ($54M) -703.5% +$81M cash QTEX QTREX Quantum Ltd. Medical Devices & Equipment $289K 5689.3% · 1y ($10M) -226.7% · 1y +$3M cash IXHL Incannex Healthcare Inc. Pharmaceuticals $86K — ($13M) -442.9% · 1y +$15M cash CNTB Connect Biopharma Holdings Limited Pharmaceuticals $64K -86.2% · 1y ($52M) -694.7% · 2y +$44M cash AVTX Avalo Therapeutics Inc. Pharmaceuticals $59K -223.2% · 4y — -97.4% +$83M cash ALT Altimmune Inc. Pharmaceuticals $41K -392.3% ($68M) -105.5% +$239M cash LYEL Lyell Immunopharma Inc. Pharmaceuticals $36K -220.9% · 1y ($151M) -38.3% +$247M cash KZIA Kazia Therapeutics Limited Pharmaceuticals $29K — ($10M) -55.5% · 2y +$49M cash ACIU AC Immune SA Pharmaceuticals as filed: CHF 4M -191.8% as filed: (CHF 70M) -53.0% as filed: (CHF 27M) AUNA Auna SA Health Care Providers & Services as filed: PEN 4.3B 14.5% as filed: PEN 544M 10.5% · 1y as filed: PEN 3.3B FMS Fresenius Medical Care AG Health Care Providers & Services as filed: €19.6B 11.7% as filed: €1.6B 8.5% as filed: €3.6B HYFT MindWalk Holdings Corp. Pharmaceuticals as filed: C$28M -96.1% as filed: (C$12M) -37.7% as filed: (C$14M) IFRX InflaRx N.V. Pharmaceuticals as filed: €29K — as filed: (€35M) -51.7% · 3y as filed: (€53M) INCR Intercure Ltd. Pharmaceuticals as filed: ₪239M -19.9% as filed: (₪71M) -3.7% as filed: ₪105M NVO Novo Nordisk A/S Pharmaceuticals as filed: DKK 309.1B 42.6% as filed: DKK 104.4B 58.5% as filed: DKK 104.5B PHG KONINKLIJKE PHILIPS NV Medical Devices & Equipment as filed: €17.8B 7.6% as filed: €903M 7.0% as filed: €4.2B PRQR ProQR Therapeutics N.V. Pharmaceuticals as filed: €16M -273.1% · 3y as filed: (€54M) — as filed: (€83M) RDY Dr. Reddy's Laboratories Ltd Pharmaceuticals as filed: ₹325.5B 13.7% as filed: ₹34.7B 10.2% as filed: (₹12.0B) SNDL SNDL Inc. Pharmaceuticals as filed: C$946M -48.8% as filed: C$58M -19.0% as filed: (C$221M) STVN Stevanato Group S.p.A. Medical Devices & Equipment as filed: €1.2B 16.8% as filed: €208M 19.1% as filed: (€141M) ZYBT Zhengye Biotechnology Holding Limited Pharmaceuticals as filed: CN¥116M 15.0% as filed: CN¥12M 5.5% as filed: (CN¥15M)